Witt Wade posted an update 1 week, 6 days ago
This specific places the linker’s S299 nearest to the actual kinase’s catalytic site, indicating in which phosphorylation would likely commence with that and also successively upstream towards DEPTOR’s degron. The actual CK1α kinase can be reportedly responsible for the particular phosphorylation of the degron, as well as each of our docking…[Read more]